Attenuation correction in single-photon emission computed tomography for NURBS-based cardiac-torso phantom using dual-energy acquisition
Hossein Rajabi, Hadi Taleshi Ahangari, Iraj Mohammadi, Alireza Mohammadkarim, Mohammad Ali Tajik-Mansoury
Journal Papers , 2020 September 1, {Pages }
Abstract
Single photon emission tomography is widely used to detect photons emitted from the patient. Some of these emitted photons suffer from scattering and absorption because of the attenuation occurred through their path in patient's body. Therefore, the attenuation is the most important problem in single-photon emission computed tomography (SPECT) imaging. Some of the radioisotopes emit gamma rays in different energy levels, and consequently, they have different counts and attenuation coefficients. Calculation of the parameters used in the attenuation equation N out= αN in= e− μ l N in by mathematical methods is useful for the attenuation correction. Nurbs-based cardiac-torso (NCAT) phantom with an adequate attenuation coefficient and activ
Cellular dosimetry of beta emitting radionuclides-antibody conjugates for radioimmunotherapy
Parisa Taheri, Hossein Rajabi, Fariba Johari Daha, Kamal Yavari, Mohammad Taghi Batiar, Hossein Mozdarani
Journal PapersIranian Journal of Nuclear Medicine , Volume 27 , Issue 2, 2019 July 1, {Pages 130-138 }
Abstract
Introduction: The choice of optimal radionuclides for radioimmunotherapy depends on several factors, especially the radionuclide and antibody. The dosimetric characteristics of a non-internalizing and an internalizing monoclonal antibody (MAb) labeled with beta emitting radionuclides were investigated.Methods: Using Geant4-DNA Monte Carlo simulation, we carry out dosimetric calculations for different subcellular distributions of beta-emitting radionuclides; 131 I, 177 Lu, 64 Cu, 186 Re and 153 Sm.Results: The dependency of theradialdose profiles on the energy spectra of electrons (beta particles and Auger and internal conversion electrons) and also their relative yield of emission is clear. The highest difference between the radionuclides t
Evaluation of the Septal Penetration and Scattering Effect in the Parallel Slat Collimator Gamma Camera On the Range Quantification in Protontherapy: Geant4 Simulation Study
Evaluation of cellular S-value of auger electrons emitting 111 in radionuclide by Geant4 and its comparison with MCNP5 Monte Carlo codes and MIRD published data.
MA Tajik-Mansoury, HT Ahangari, H Rajabi, M Jadidi
Verification of Activity Accumulation Location Effect in Patients Treated with I-131 Radio Pharmacy on the Evaluated Exposure at Different Distances from Patient using NCAT Phantom
Journal Papersscientific journal of ilam university of medical sciences , Volume 25 , Issue 6, 2018 March 15, {Pages 54-62 }
Abstract
Discussion & Conclusions: Distinct TEDE values must be defined for each of the aforementioned organs and confirmed before releasing patients who will be faced to the others at short distances. Otherwise, guidelines must be considered for the others who will be faced to the released patient.
Verification of Activity Accumulation Location Effect in Patients Treated with I-131 Radio Pharmacy on the Evaluated Exposure at Different Distances from Patient usi...
Journal Papersscientific journal of ilam university of medical sciences , Volume 25 , Issue 6, 2018 March 15, {Pages 54-62 }
Abstract
Discussion & Conclusions: Distinct TEDE values must be defined for each of the aforementioned organs and confirmed before releasing patients who will be faced to the others at short distances. Otherwise, guidelines must be considered for the others who will be faced to the released patient.
Journal PapersJournal of cancer research and therapeutics , Volume 14 , Issue 3, 2018 April 1, {Pages 647 }
Abstract
> AbstractPurpose: GATE/GEANT is a Monte Carlo code dedicated to nuclear medicine that allows calculation of the dose to organs (bone and bone marrow) of voxel phantoms. On the other hand, Medical Internal Radiation Dose (MIRD) is a well-developed system for estimation of the dose to human organs. In this study, results obtained from GATE/GEANT using leg of Snyder phantom is compared to published MIRD data.Materials and Methods: For this, the mathematical leg of Snyder phantom was discretized and converted to a digital phantom of 100? 100? 200 voxels. The activity was considered uniformly distributed within bone and bone marrow. The GATE/GEANT Monte Carlo code was used to calculate the dose to the bone and bone marrow of the leg phantom fro
A comparison between track-structure, condensed-history Monte Carlo simulations and MIRD cellular S-values
MA Tajik-Mansoury, H Rajabi, H Mozdarani
Journal PapersPhysics in Medicine & Biology , Volume 62 , Issue 5, 2017 February 8, {Pages N90 }
Abstract
The S-value is a standard measure in cellular dosimetry. S-values are calculated by applying analytical methods or by Monte Carlo simulation. In Monte Carlo simulation, particles are either tracked individually event-by-event or close events are condensed and processed collectively in different steps. Both of these methods have been employed for estimation of cellular S-values, but there is no consistency between the published results. In the present paper, we used the Geant4-DNA track-structure physics model as the reference to estimate the cellular S-values. We compared the results with the corresponding values obtained from the following three condensed-history physics models of Geant4: Penelope, Livermore and standard. The geometry and
Purpose: Respiration causes lesion smearing, image blurring and quality degradation, affecting lesion contrast and the ability to define correct lesion size. The spatial resolution of current multi pinhole SPECT (MPHS) scanners is sub‐millimeter. Therefore, the effect of motion is more noticeable in comparison to conventional SPECT scanner. Gated imaging aims to reduce motion artifacts. A major issue in gating is the lack of statistics and individual reconstructed frames are noisy. The increased noise in each frame, deteriorates the quantitative accuracy of the MPHS Images. The objective of this work, is to enhance the image quality in 4D‐MPHS imaging, by 4D image reconstruction. Methods: The new algorithm requires deformation vector
Synthesis and Biological Evaluation of 99mTc-Chitosan Nanoparticles as a Potential Radiopharmaceutical for Liver Imaging
Hossein Rajabi, Samira Rasaneh, Saleh Salehi
Journal PapersSynthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry , Volume 46 , Issue 10, 2016 October 2, {Pages 1450-1454 }
Abstract
Nanoparticles are generally cleared by the reticuloendothelial system, taken up by Kupffer cells in liver. This principle can be used for liver imaging. Chitosan is an excellent biocompatible and biodegradable polymer. In this study, the authors synthesized 99mTc-chitosan nanoparticles and evaluated its potential for liver imaging. Chitosan nanoparticles were synthesized and radiolabeled with 99mTc. The labeling efficiency, stability, biodistribution, and imaging study in the normal mice was performed. Biodistribution and imaging studies demonstrated an efficient accumulation of the radiolabeled nanoparticles in the mice liver and indicated the 99mTc-chitosan nanoparticles may be considered as a promising radiopharmaceutical for liver imagi
دزيمتري راديونوكلئيدهاي تجمع يافته در لايه هاي ديواره مثانه در مقياس ماكرسكوپيك و ميكروسكوپيك با روش شبيه سازي مونت كارلو.
1398
اريان, فاطمه
تعيين محل مناسب قرارگيري دزيمتر هنگام استفاده همزمان از روپوش سربي و دزيمتر شخصي؛ مطالعه اي با استفاده از شبيه سازي مونت كارلو.
1399
سرفان, محمد غني
بررسي امكان استفاده از تابش هاي چرنكوف در تعيين دز تابشي در هنگام راديونوكلئيد تراپي با اكتينيوم -225 ،توريوم-227 و راديوم-223، يك مطالعه شبيه سازي مونت كارلو
1396
ابراهيمي فرد, علي
پيش بيني دز جذبي تومور قبل از درمان 177Lu براي بيماران با تومورهاي نورواندوكرين بر پايه روش راديوميكس
1397
باقرزاده, سعيد
بررسي كمي و كيفي پديده بازگشت الكترون در ميدان هاي مغناطيسي خارجي و تاثير آن در توزيع دوز الكترون هاي ثانويه ناشي از تابش هاي فوتوني، پروتوني و يون هاي كربن
1399
الشريفي, حسين حميد نوري
برآورد دز جذبي دست كاركنان بخش هاي پزشكي هسته اي با استفاده از فانتوم هاي وكسلي دست و شبيه سازي مونت كارلو
1399
بداقي حسين ابادي, رقيه
بررسي امكان مونيتورينگ بلادرنگ دوز در پرتودرماني با باريكه هاي فوتوني و پروتوني با استفاده از القا پوزيترون در حضور نانوذرات با تصوير برداريPET :يك مطالعه شبيه سازي